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How Analytics Transformed Kenalog Billing — and Why STAR² Ai Is Setting a New Standard for Revenue Capture

August 15, 2025

Billing for single-use vial medications like J3301 (Kenalog) injections has always been a challenge. The process is complex, payor rules evolve, and even the most diligent physicians can miss revenue opportunities simply by the way units are recorded. But when physician workflows, expert coders, and advanced analytics come together, the results are transformative.

Recently, one of our clients highlighted just how powerful this combination can be. And it’s exactly the type of story that underscores why STAR² Ai is outperforming even the most optimistic forecasts for revenue-cycle AI.

The Data Story: Finding Revenue in Plain Sight

A closer look at the numbers from early 2025 shows the scale of the opportunity:

  • Doctors recorded 146,312 J3301 units
  • Coders billed 269,147 units — an 84% increase
  • Data uncovered the potential for 15,981 additional units

This isn’t about pointing fingers. Physicians are focused on patient care. Coders are trained to capture every allowable unit. But even then, hidden opportunities remain. Analytics provided the missing link — finding the “last mile” of revenue that would have been invisible without data-driven insight.

From a Single Case to a Broader Impact

This Kenalog example is just one story in a much larger transformation taking place across healthcare. It reflects the same dynamics that STAR² Ai delivers at scale:

  • More captured revenue without more work.
  • Sustained EBITDA gains validated in the real world.
  • A bridge between what physicians record, what coders capture, and what practices actually earn.

White Plume recently announced that STAR² Ai 2.8 is delivering validated EBITDA gains of $29,266 per physician per year, with the potential to exceed $63,000 by early 2026. To put that in perspective, industry analyses suggest that even a “perfect” coding-automation solution might generate only $8,000–$9,000 per physician by 2027. STAR² Ai has already tripled that benchmark today.

Why STAR² Ai Outperforms

The success behind both the Kenalog case study and the national results lies in three factors:

1. Exclusive Specialty Data — STAR² Ai is trained on millions real-world ambulatory encounters across seven high-value specialties. That depth of longitudinal, specialty-specific data creates precision that synthetic or generic AI cannot replicate.

2. Hybrid Agentic AI — By combining advanced reasoning with deterministic coding rules, STAR² Ai automates up to 80% of manual coding tasks while ensuring compliance. This hybrid approach doesn’t just speed up coding — it maximizes net revenue capture.

3. Seamless Workflow Integration — Physicians record care as they always have. Coders receive optimized claims. No extra clicks, no added friction. Value appears in 60–90 days, with most practices achieving full ROI in under three months.

The Bigger Picture: Avoiding the $55K Silent Loss

Every year, practices that wait for generic automation tools are silently leaving $55,000 per physician on the table. That loss is invisible in CFO dashboards, but it’s painfully real in physician operating margins. STAR² Ai closes that gap now — and the Kenalog example proves just how much opportunity is hiding in plain sight.

The Takeaway

The story of 146,312 recorded units becoming 269,147 billed — with another 15,981 waiting to be captured — is more than just a case study. It’s evidence of what happens when advanced analytics shine a light on hidden opportunity.

At White Plume, we believe every unit matters. STAR² Ai doesn’t just promise future value — it delivers immediate, validated EBITDA gains today.

Result: More captured revenue. Less missed opportunities. And for our clients, that translates into millions of dollars of lasting enterprise value.

Ready to see the impact White Plume can have on your organization? Schedule a demo to learn how we help you drive revenue and EBITDA gains.